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Showing posts with the label Oncology

Zanidatamab-hrii India Price & Patient Access Guide

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  Zanidatamab (Ziihera) 300 mg Injection available in India A diagnosis of HER2-positive biliary tract cancer can present significant treatment challenges, particularly when the disease has progressed despite previous therapy. For eligible patients, advances in targeted cancer treatment have created new options that focus on specific molecular characteristics of the tumor rather than relying solely on conventional treatment approaches. Zanidatamab-hrii is a HER2-directed bispecific antibody developed to target HER2-positive cancer cells through a dual-binding mechanism. Unlike therapies that interact with a single target site, Zanidatamab binds to two distinct extracellular domains of the HER2 receptor. This dual engagement promotes receptor internalization and reduces HER2 expression on the tumor cell surface. In addition, Zanidatamab activates multiple immune-mediated pathways involved in cancer cell elimination, including complement-dependent cytotoxicity (CDC), antibody-depend...

Myth vs Fact: Blincyto Edition

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Blinatumomab (Blincyto) in India Blincyto is a Bispecific T-cell engager (BiTE) immunotherapy used for the treatment of certain B-cell precursor acute lymphoblastic leukemia (ALL). Since it works differently from chemotherapy, it has led to curiosity and confusion. These confusions lead to misconceptions to patients, so here’s the article to burst the myth and present the facts. MYTH: Blincyto ( Blinatumomab ) works for all types of leukemia FACT: Blincyto is indicated in adults and children above one month old with: CD19-positive B-cell precursor acute lymphoblastic leukemia (ALL) in first or second complete remission with minimal residual disease (MRD) greater than or equal to 0.1%.   Relapsed or refractory CD19-positive B-cell precursor acute lymphoblastic leukemia (ALL).  CD19-positive Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia (ALL) in the consolidation phase of multiphase chemotherapy.  MYTH: Side-effects of Blincyto are sam...